As an independent science, biochemistry began to develop in the second half of the XIX century. The term “biochemistry” was first proposed in 1882 by Alexander Yakovlevich Danilevsky (1838-1923). The founder of domestic biochemistry is rightly considered to be O.Ya. Danilevsky, a pupil of Kharkiv University who founded the national school of biochemists.
The Department of Biochemistry was organized in 1938 on the initiative of a corresponding member of the Academy of Sciences of Ukraine, winner of the prize. O.V. Palladin, Honored Scientist
Of Ukraine, Doctor of Biological Sciences, Professor Aron Mikhailovich Utevsky. In 1936, at the initiative of A.M. Utevsky, biochemistry as an independent subject was first included in the system of pharmacists (still at the Department of Hygiene) and he himself taught this course at the Kharkiv Pharmaceutical Institute. A.M. Utevsky began his scientific activity in 1925 at the Department of Biochemistry of the Kharkiv Medical Institute under the leadership of the outstanding biochemist O.V. Palladin (later President of the USSR Academy of Sciences). From 1967 to 1991, the Department of Biochemistry is located in the building of the Kharkiv Pharmaceutical Institute on the Pushkinska street, 27.
Heads of the department
From 1938 to 1941 the Department of Biochemistry of the Kharkiv Pharmaceutical Institute was headed by Professor L.M. Makarevich-Halperina. In 1936, L.M. Makarevich-Halperina defended her dissertation on “Data on nucleotide metabolism in the heart muscle.” In 1938 she was approved as an associate professor of biochemistry. In October 1941 she was evacuated to Kazakhstan and in December 1943 she returned to the position of the head of the Department of Biochemistry of the KPI, where she worked until June 1952. In 1946, L.M. Makarevich-Halperina defended her dissertation for the degree of Doctor of Medical Sciences on “Data on the chemical composition of the heart when its function changes.” In 1948 she was awarded the academic title of professor. Since 1933 she has participated in the All-Union and Ukrainian Congresses of Physiologists, Biochemists and Pharmacologists. She was a member of the board of the Ukrainian Union of Physiologists, Biochemists and Pharmacologists (1930-1952).
In 1954-1961, the head of the Department of Biochemistry of the Kharkiv Pharmaceutical Institute was Professor Evdokia Khomivna Ivanenko. In 1955, E. Kh. Ivanenko defended her dissertation for the degree of Doctor of Biological Sciences on “The effect of anesthesia on the processes of carbohydrate metabolism in the brain.” In 1956 he was awarded the academic title of professor.
Under her supervision, one candidate’s dissertation was completed, one educational and methodical manual was published, two monographs “Vitamins” and “Biochemistry of the brain under anesthesia”, 35 scientific articles were published. In 1961, E. Ivanenko was dismissed from the post of head of the Department of Biochemistry of the KPI in connection with her election to the Zhdanov A.A. Leningrad State University.
In 1962, the departments of biochemistry and physiology were merged. The combined department was headed by physiologists: Professor T.G. Yefimova, and since 1969 – Professor L.D. Khaleeva. From 1962 to 1977 the head of the course of biochemistry at the Department of Anatomy and Physiology of the Kharkiv Pharmaceutical
Institute was Associate Professor Veronika Fyodorovna Desenko. In 1961 she defended her dissertation on “Study of the nitrogen composition and physicochemical properties of brain colloids in the excitation and inhibition of nervous activity caused by pharmacological agents.”
After the defense of the candidate’s dissertation, scientific work was carried out in the biopharmaceutical field of evaluation of new dosage forms together with the Department of Drug Technology. She was awarded the honorary awards “Excellence in Health”, “Excellence in Higher Education”.
During 1977-1987, the Department of Biochemistry was headed by Professor Ninel Mykolaivna Madievska. In May 1951 she defended her dissertation for the degree of Candidate of Medical Sciences on “Exchange of adrenaline in obliterating endoarteritis” under the guidance of Corresponding Member. NAS of Ukraine, Professor A.M. Utevsky.
In 1975 she defended her dissertation for the degree of Doctor of Medical Sciences on “Biochemical parameters of homeostasis in patients with vesicles, lupus, eczema and psoriasis.” In 1979 N.M. Madievskaya was awarded the title of professor of the department. From 1988 to 1996 she worked as a professor at the Department of Biochemistry and Professor-Consultant.
From 1987 to 1991, the staff of the Department of Biochemistry of the Kharkiv Pharmaceutical Institute was headed by Oleksandr Kyrylovych Gulevsky.
In 1973 he defended his dissertation, working as a junior researcher in the Department of Cryobiology of the Institute of Cryobiology and Cryomedicine of the USSR Academy of Sciences. Since 1977 he has been a senior researcher, and since 1986 he has been the head of the Laboratory of Molecular Cryobiology of the IPKiK of the
USSR Academy of Sciences. In 1986 he defended his doctoral dissertation. In 1988 he was awarded the title of professor. For the series of works “Mechanism of cryodamage of biomembranes” together with the Institute of Problems of Cryobiology and Cryomedicine of the USSR Academy of Sciences received the award of the USSR Academy of Sciences. O.V. Palladin in the field of biochemistry.
During 1991-2010, the Department of Biological Chemistry was headed by Professor Larysa Mykolayivna Voronina. She began her scientific career as an assistant at the Department of Biochemistry of the Kharkiv Zooveterinary Institute. In 1967 she defended her dissertation on “Dynamics of protein and nucleic acids in the tissues of turkeys in connection with age and functional status of the organism.”
Since 1968, Larysa Mykolayivna’s life has been closely connected with the Institute of Pharmacy, and later with the National University of Pharmacy, where she first worked as an assistant (1968-1977), senior lecturer (1977-1981), associate professor (1981-1991). years), and in 1991-2010 as head and professor of biochemistry.
L.M. Voronina defended her doctoral dissertation on “Biological activity and mechanisms of action of some sulfo-derived dicarboxylic acids as a new series of non-hormonal sugar-lowering compounds” in 1993.For more than 30 years, Larysa Mykolayivna has always worked as the Scientific Secretary of NUPh (1977-2008).
For many years of work L.M. Voronina was awarded the badges of the Ministry of Health of the USSR “Excellence in Health”, as well as “For outstanding achievements in higher education in the USSR” and “Inventor of the USSR”. In 2008, L.M. Voronina was awarded the Honorary Title of “Honored Worker of Education of Ukraine”, which was awarded by the President of Ukraine.
In 2010-2018, the department was headed by Doctor of Biological Sciences, Professor Andriy Leonidovych Zagayko. In 1996 he graduated with honors from Kharkiv State University with a degree in biochemistry. In 2000, after graduating, he defended his dissertation for the degree of Candidate of Biological Sciences on “System of lipid transport in oxidative stress in rats”, worked at the Department of Biological Chemistry at Karazin V.N. KhNU. Since 2002 he has been working at the National University of Pharmacy as an assistant, and in the same year – as an associate professor of biological chemistry. In 2009 he defended his doctoral dissertation on “The role of antioxidants of natural origin in the correction of lipid metabolism disorders under stress” and in 2011 received the title of Professor of Biological Chemistry.
A.L. Zagayko is the author of the monographs “Metabolic syndrome: mechanisms of development and prospects of antioxidant therapy” (2007), “Prospects for the use of natural antioxidants in the prevention of atherosclerosis” (2010), “Biologically active substances of grapes” (2012); textbooks “Chemical interactions in wildlife” (2000), and co-author of educational and methodical works: “Clinical Biochemistry” (2003), “Laboratory and seminar classes in biological chemistry” (2004), “Fundamentals of Biochemical Engineering ”(2004),“ Biomolecules – Pharmaceuticals ”(2008),“ Functional Biochemistry ”(2010),“ Biological Chemistry ”(2011). A.L. Zagayko is the author and co-author of more than 150 scientific papers, including: four patents, one information letter, 80 scientific articles, 23 articles in the Pharmaceutical Encyclopedia, 50 abstracts, nine textbooks (one of which in English). Since 2010 he has been a member of the Academic Council of NUPh and in the same year he became the Deputy Editor-in-Chief of the Ukrainian Biopharmaceutical Journal, and since 2011 he has been a member of the Specialized Academic Council of NUPh, majoring in Pharmacology. Since 2012 he has been a member of the editorial board of the European journal Adipobiology. A.L. Zagayko – since 2000 is a full member of the Federation of European Biochemical Societies (FEBS), since 2005 – a member of the European Association for the Study of Diabetes (EASD) and Atherosclerosis (EAS), the American Diabetes Association (ADA), since 2010 – member of the European Council of Pharmacological Societies (EUFEPS), and since 2012 – member of the Presidium of the European Society of Adipobiology and Adipopharmacology (EUAA). Scientific and pedagogical activity of A.L. Zagayko was awarded a diploma of the Kharkiv Regional State Administration, thanks and diplomas of NUPh. In 2002, 2004, 2006 he received EASD (European Association for the Study of Diabetes) grants.
From February 2020 to October 2020, the department was headed by Candidate of Biological Sciences, Associate Professor Anna Borisovna Kravchenko. In 1991 she started working at the Kharkiv Pharmaceutical Institute as a senior laboratory assistant, which she combined with the position of assistant. Since 2002 – Assistant Professor of Biochemistry, and from 2003 to present – Associate Professor of Biochemistry. From 2006 to 2019 she served as a methodologist and head of the educational part of the department. In 2010 she defended her dissertation for the degree of Candidate of Biological Sciences in “Biochemistry” on “The effect of antioxidants of plant origin on the metabolism of nitrogen-containing compounds under neurogenic stress in rats.” He is B2 Cambridge English: First (FCE) certified.
G.B. Kravchenko is a co-author of textbooks Clinical Biochemistry (2005), Biomolecules – Pharmaceuticals (2008), Journal for laboratory works on biochemistry (2009), Functional Biochemistry (2009), Biological Chemistry (2011) ), Laboratory Manual on Biochemistry (2012) and others. Constantly participates in the creation of working programs in biochemistry, clinical biochemistry, functional biochemistry and biochemistry of pathological conditions for various specialties. He is a co-author of standard programs of disciplines: “Biological Chemistry” and “Clinical Biochemistry” for the specialty “Clinical Pharmacy”, “General Biochemistry and Molecular Biology” for the specialty “Pharmaceutical Technology” and elective courses “Functional Biochemistry” and “Environmental Biochemistry” . He has 24 co-authorships in educational and methodical publications of the department. In 2014 she graduated from NUPh with a degree in “Pedagogy and Psychology of Higher Education” and received a master’s degree with honors. G.B. Kravchenko’s research work was devoted to the study of hypoglycemic and antithyroid activity of synthetic compounds. Currently, the priority scientific direction of her research is the study of biochemical mechanisms of development of proatherogenic conditions and free radical pathologies. G.B. Kravchenko is the co-author of more than 100 scientific publications, six patents, and five monographs “Prospects for the use of natural antioxidants in the prevention of atherosclerosis” (2010), “Biologically active substances of grapes and health” (2012). He is the author of 4 publications in publications that are part of the scientific-metric databases Scopus or Web of Science. Has passed 5 cycles of advanced training, including professional on Clinical biochemistry in the EU country – Slovakia (Pavol Safarik University in Kosice / Univerzitna nemocnica L.Pasteura). Anna Borysivna is a member of the international scientific organizations of the European Association for the Study of Diabetes (EASD) and the International Biochemical Society (FEBS). In 2018 she was awarded the Diploma of the Executive Committee of the Kharkiv City Council.
From October 2020 to the present, the department is headed by Doctor of Biological Sciences, Professor Vira Mykolayivna Kravchenko. He is a current member of the editorial boards of the journals “Ukrainian Biopharmaceutical Journal” and “Ukrainian Journal of Clinical and Laboratory Medicine”, a member of the approbation council in the specialty
14.03.05. – Pharmacology, Academic Council and CMR, Council of the Faculty of Medical and Pharmaceutical Technologies of NUPh, Member of the Ukrainian Biochemical Society, which is a member of the Federation of European Biochemical Societies (FEBS). She was awarded the Diploma of the Kyiv City Council of Kharkiv on the occasion of the 200th anniversary of the University, the Diploma of the Department of Health HODA on the occasion of the day of the pharmaceutical worker (2017); Honorary diploma of NUPh on the occasion of the 80th anniversary of the founding of the Department of Biological Chemistry (2018), diplomas of KPI. In 2010, the name of Kravchenko V.N. was included in the “Golden Book of Honor” for a significant contribution to the development of the university, pharmaceutical education and science, training for Ukraine and the world.
V.M. Kravchenko is the author and co-author of more than 180 scientific papers, including 4 patents, copyright certificates and 40 educational publications, including publications for students majoring in “Pharmacy”, “Clinical Pharmacy”, “Perfume Technology”. cosmetics “,” Laboratory diagnostics “,” Biotechnology “,” Technology of pharmaceuticals “: textbooks” Biological Chemistry “in Russian. and Ukr. languages, “Guides for laboratory and seminar classes in biological chemistry”, textbooks: “Clinical Biochemistry”, “Biology with the basics of genetics”, “Cell Biology”, “Fundamentals of Histology”, as well as a co-developer of standard and work programs in various disciplines. V.M. Kravchenko’s research work will be carried out in experimental studies to study the thyroid activity of new synthesized compounds. types of pharmacological activity, biochemical mechanisms of action of active compounds. In particular, Vira Mykolayivna is a co-author of 12 scientific articles, which are published in foreign rating scientific journals that are part of the scientific and metric database SCOPUS. According to the results of the most frequently cited articles in the journal “Chemistry of Heterocyclic Compounds” in 2008 – 2009 entered the TOP 10. Constantly participates in national congresses, congresses (biochemical, pharmacists, pharmacologists), scientific conferences, methodological seminars , meetings, etc., is constantly improving its professional level.
Scientific and pedagogical staff of the department in different years
The department today
Staff: head of the department, doctor of biological sciences, professor of the department Kravchenko Vira Mykolayivna; Doctor of Biological Sciences, Professor of the Department Maloshtan Lyudmila Mykolayivna; Candidate of Biological Sciences, Associate Professor Kravchenko Anna Borysivna; Candidate of Pharmaceutical Sciences, Associate Professor Senyuk Igor Valerievich; Candidate of Biological Sciences, Associate Professor Krasilnikova Oksana Anatoliyivna; Candidate of Pharmaceutical Sciences, Associate Professor Galuzinska Lyubov Valeriyivna; Candidate of Biological Sciences, Associate Professor Filimonenko Victoria Pavlovna; Candidate of Biological Sciences, Assistant Briukhanova Tetyana Oleksandrivna; candidate of biological sciences, assistant Lytkin Dmytro Vitaliyovych; Candidate of Pharmaceutical Sciences, Assistant Tkachenko Oksana Volodymyrivna; Candidate of Biological Sciences, Assistant Storozhenko Galyna Valeriivna; senior laboratory assistant Natalia Eduardivna Bushlya.
On September 9, 2018, Professor Andriy Leonidovych Zagayko was awarded a diploma for fruitful work on providing quality pharmaceutical education on the occasion of the Day of the Pharmaceutical Worker. Solemn awarding from the rector of NUPh Alla Kotvitska and the Governor of Kharkiv region.
On December 20, 2018, the university administration in the person of the rector prof. Kotvitskaya Alla Anatoliyivna congratulated the Department of Biological Chemistry on the 80th anniversary of the department.
Associate Professor Kravchenko Anna Borisovna visited May 26-29, 2019, the 87th Congress of the European Atherosclerotic Society (EAS), which took place in Maastricht (Netherlands). This year’s Congress attracted more than 2,000 delegates from 70 countries.
August 28, 2019 thanks to the Prime Minister of Ukraine Volodymyr Groysman for significant personal achievements in professional activities, ensuring the implementation of state policy in the fields of health, education and science, active participation in the training of specialists, scientific, scientific and pedagogical staff and Igor Senyuk, Associate Professor of the Department of Biological Chemistry, was awarded for impeccable work.
On January 30, 2020 Assoc. Oksana Volodymyrivna Shovkova was awarded a diploma of Candidate of Pharmaceutical Sciences at the Academic Council of the University.
On April 2, 2021, important events for the department took place – defense of the dissertation for the degree of Doctor of Pharmaceuticals Olena Dolzhikova under the supervision of Professor Lyudmila Maloshtan and defense of the dissertation for the degree of Candidate of Pharmaceutical Sciences Bashar Jabar Ali Al-Sahlani .under the supervision of Associate Professor Igor Senyuk.
The Department of Biological Chemistry welcomes you
The Department of Biological Chemistry is a fundamental department of the medical-biological cycle, located in the building on Melnykova 12. The department was organized in 1938 on the initiative of the Doctor of Biological Sciences, Professor A.M. Utevsky. There are now 11 teachers working at the department, one of whom is a doctor of science – AL. There are 10 candidates of science, including 8 associate professors and 2 assistants. Three senior laboratory assistants are involved in the preparation of the educational process. At the Department of Biological Chemistry for students of 2-4 courses are taught in the licensed areas and specialties a number of disciplines: “Biological Chemistry”, “Clinical Biochemistry”, “Functional Biochemistry”, “General Biochemistry and Molecular Biology”, “General Biochemistry” The Student Science Society attracts about 30 students each year for biochemical and pharmacological research at the department. Research work occupies one of the leading positions in the activity of the department, the main directions of which currently include: biological activity and some mechanisms of action of synthetic and natural compounds as potential drugs; study of acute and chronic toxicity of biologically active substances of natural origin; study of biochemical mechanisms of development of pathologies accompanied by dyslipidemic conditions (stress, metabolic syndrome, diabetes, atherosclerosis) and search for ways of their correction; development of biochemical criteria for evaluation of biological activity of drugs. “Biological Chemistry” is included in the list of disciplines that are presented for the examination of the integrated examination “KROK-1. Pharmacy”